| Gruppo A 1. Porto 2. Paris Saint Germain 3. Dinamo Kiev 4. Dinamo Zagabria | Gruppo C |
| Gruppo B 1. Arsenal 2. Schalke 04 3. Montpellier 4. Olympiacos | Gruppo D 1. Real Madrid 2. Borussia Dortmund 3. Manchester City 4. Ajax Amsterdam |
| 1a giornata (18.9.2012) Dinamo Zagabria-Porto Paris Saint Germain-Dinamo Kiev Montpellier-Arsenal Olympiacos-Schalke 04 Málaga-Zenit Milan-Anderlecht Borussia Dortmund-Ajax ) Real Madrid-Manchester City | 4a giornata (6.11.2012) Dinamo Kiev-Porto Paris Saint Germain-Dinamo Zagabria Schalke 04-Arsenal Olympiacos-Montpellier Anderlecht-Zenit Milan-Málaga Manchester City-Ajax Real Madrid-Borussia Dortmund | |
| 2a giornata (3.10.2012) Dinamo Kiev-Dinamo Zagabria Porto-Paris Saint Germain Schalke 04-Montpellier Arsenal-Olympiacos Anderlecht-Málaga Zenit-Milan Manchester City-Borussia Dortmund Ajax-Real Madrid | 5a giornata (21.11.2012) Porto-Dinamo Zagabria Dinamo Kiev-Paris Saint Germain Arsenal-Montpellier Schalke 04-Olympiacos Zenit-Málaga Anderlecht-Milan Ajax-Borussia Dortmund Manchester City-Real Madrid | |
| 3a giornata (24.10.2012) Porto-Dinamo Kiev Dinamo Zagabria-Paris Saint Germain Arsenal-Schalke 04 Montpellier-Olympiacos Zenit-Anderlecht Málaga-Milan Ajax-Manchester City Borussia Dortmund-Real Madrid | 6a giornata (4.12.2012) Dinamo Zagabria-Dinamo Kiev Paris Saint Germain-Porto Montpellier-Schalke 04 Olympiacos-Arsenal Málaga-Anderlecht Milan-Zenit Borussia Dortmund-Manchester City Real Madrid-Ajax |
| Gruppo E 1. Shakhtar Donetsk 2. Chelsea 3. Juventus 4. Nordsjælland | Gruppo G 1. Barcellona 2. Celtic Glasgow 3. Benfica 4. Spartak Mosca |
| Gruppo F 1. BATE Borisov 2. Bayern Monaco 3. Valencia 4. LOSC Lille | Gruppo H 1. Manchester United 2. R 1907 Cluj 3. Sporting Braga 4. Galatasaray |
| 1a giornata (19.9.2012) Shakhtar Donetsk-Nordsjælland Chelsea-Juventus LOSC Lille-BATE Borisov Bayern Monaco-Valencia Barcellona-Spartak Mosca Celtic-Benfica Manchester United-Galatasaray Sporting Braga-R 1907 Cluj | 4a giornata (7.11.2012) Juventus-Nordsjælland Chelsea-Shakhtar Donetsk Valencia-BATE Borisov Bayern Monaco-LOSC Lille Benfica-Spartak Mosca Celtic-Barcellona R 1907 Cluj-Galatasaray Sporting Braga-Manchester United | |
| 2a giornata (2.10.2012) Juventus-Shakhtar Donetsk Nordsjælland-Chelsea Valencia-LOSC Lille BATE Borisov-Bayern Monaco Benfica-Barcellona Spartak Mosca-Celtic R 1907 Cluj-Manchester United Galatasaray-Sporting Braga | 5a giornata (20.11.2012) Nordsjælland-Shakhtar Donetsk Juventus-Chelsea BATE Borisov-LOSC Lille Valencia-Bayern Monaco Spartak Mosca-Barcellona Benfica-Celtic Galatasaray-Manchester United R 1907 Cluj-Sporting Braga | |
| 3a giornata (23.10.2012) Nordsjælland-Juventus Shakhtar Donetsk-Chelsea BATE Borisov-Valencia LOSC Lille-Bayern Monaco Spartak Mosca-Benfica Barcellona-Celtic Galatasaray-R 1907 Cluj Manchester United-Sporting Braga | 6a giornata (5.12.2012) Shakhtar Donetsk-Juventus Chelsea -Nordsjælland LOSC Lille-Valencia Bayern Monaco-BATE Borisov Barcellona-Benfica Celtic-Spartak Mosca Manchester United-R 1907 Cluj Sporting Braga-Galatasaray |
